Abstract

This chapter presents the development of a second-generation small-animal Single-photon emission computed tomography (SPECT) - magnetic resonance (MR) insert that overcomes the shortcomings of the first-generation insert. Currently, the most exciting developments in multimodality imaging are dual-modality Positron emission tomography (PET)/magnetic resonance imaging (MRI) and SPECT/MRI. High-resolution MR images and their ability to differentiate between soft tissues can be exploited in quantitative PET and SPECT image reconstruction when partial volume effect from differential radioactivity uptake in adjacent tissues is important. Modern PET/CT and SPECT/CT scanners, in a coplanar configuration, share the same gantry and the scanning table transports the patient between the different modalities. The SPECT/MR insert demonstrated the feasibility of simultaneous SPECT/MRI with both phantom …

Metadata

publication

Hybrid Imaging in Cardiovascular Medicine, 57-74, 2017

year

2017

publication date

2017/10/31

authors

Benjamin MW Tsui, Jingyan Xu, Andrew Rittenbach, James W Hugg, Kevin B Parnham

link

https://www.taylorfrancis.com/chapters/edit/10.1201/9781315374031-3/development-second-generation-whole-body-small-animal-spect-mr-imaging-system-benjamin-tsui-jingyan-xu-andrew-rittenbach-james-hugg-kevin-parnham

book

Hybrid Imaging in Cardiovascular Medicine

pages

57-74

publisher

CRC Press