Abstract

46
Objectives
To develop a new approach for modeling and compensating for the spatially variant point response function (PRF) for small animal pinhole SPECT
Methods
We pre-calculate and store the system matrix (SM) generated at a subvoxel density (dense SM, dSM) at one projection view; the SM at all projection views can be obtained from a recombination of the dSM entries. The dSM generation only needs knowing the intrinsic parameters of the pinhole collimator. Imaging configurations with the same intrinsic but different extrinsic parameters can reuse the same dSM. Unlike the rotation-based projector, the dSM approach replaces the image rotation step by a SM rotation at the subvoxel density. The higher the subsample factor, the higher the PRF calculation accuracy and the longer the run-time computation. We evaluate the PRF accuracy of using different subsample factors and their effects on the …

Metadata

publication

Journal of Nuclear Medicine 56 (supplement 3), 46-46, 2015

year

2015

publication date

2015/5/1

authors

Jingyan Xu, Andrew Rittenbach, Andrea Fabbri, Valentino Orsolini Cencelli, Benjamin Tsui

link

https://jnm.snmjournals.org/content/56/supplement_3/46.short

source

Journal of Nuclear Medicine

volume

56

issue

supplement 3

pages

46-46

publisher

Society of Nuclear Medicine