Abstract

We investigated the performance of a post reconstruction dual respiratory and cardiac (R&C) motion compensation method for improved image quality of 4D cardiac gated small animal myocardial perfusion (MP) SPECT images. A normal mouse was injected with ~8 mCi of Tc-99m sestamibi, anesthetized, fitted with ECG leads for cardiac gating signal acquisition, and placed on top of a pressure gauge bellow for respiratory motion measurements. A 2-hour list-mode dataset was acquired using a MILab small animal SPECT system fitted with a multi-pinhole collimator with 0.4 mm resolution in 5-minute sections. They were subsequently sorted for different acquisition times and reconstructed using a vendor provided OS-EM algorithm with simultaneous 6 respiratory and 8 cardiac equal-time gates over each motion cycle. Using a group-wise B-spline non-rigid image-based registration method, the deformation fields of …

Metadata

publication

2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC …, 2015

year

2015

publication date

2015

authors

Taek-Soo Lee, Andrew Rittenbach, Tao Feng, Benjamin MW Tsui

link

https://ieeexplore.ieee.org/abstract/document/7582214/

conference

2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)

pages

1-4

publisher

IEEE