Abstract

2119
Objectives
The goal was to evaluate a direct regional activity characterization approach (DRAC) and compare it with 3 other methods for focal uptake (FU) estimation in pinhole SPECT.
Methods
The DRAC approach [1] assumes the intensity distribution of a FU image can be modeled as a Gaussian function and estimates the FU activity using a new iterative ML (v+g) algorithm. This work focused on FU activity estimation using simulations in single pinhole (SPH) SPECT applications. A phantom consisting of a cylinder with 15 mm diameter and 20 mm height, and a 3 mm diameter sphere placed at the center of the FOV and 12 mm from the cylinder’s center, was used in this study. Analytical projections of the phantom were generated with a dual head SPH SPECT geometry. To simulate FU variations, cylinder-to-sphere activity ratios were varied. For each variation, Poisson noise was added to the projections at 5 …

Metadata

publication

Journal of Nuclear Medicine 55 (supplement 1), 2119-2119, 2014

year

2014

publication date

2014/5/1

authors

Andrew Rittenbach, Jingyan Xu, Chi Liu, Mahmoud Razavian, Mehran Sadeghi, Benjamin Tsui

link

https://jnm.snmjournals.org/content/55/supplement_1/2119.short

source

Journal of Nuclear Medicine

volume

55

issue

supplement 1

pages

2119-2119

publisher

Society of Nuclear Medicine